Different genomic mutations signatures are associated to specific PD-L1/TMB states on lung cancer with potential value for patients screening for immunotherapy
- Autor:D'Argenio V, Salvatore F.
- Data da Publicação:May 28, 2020
- Type:Journals
- DOL:10.1016/j.hfc.2018.03.008.
- Publicado em:Heart Fail Clin.
- Volume/Issue:14/(3)
Abstract
Within the last years, exercise training and rehabilitation as add-on to medical treatment has become an emerging field in pulmonary hypertension. Owing to the beneficial effects of exercise training in pulmonary hypertension, the new European Respiratory Society/European Society of Cardiology guidelines for pulmonary hypertension recommended a supervised and closely monitored exercise and respiratory training/rehabilitation as add-on to medical therapy (class IIa, level of evidence B). In this article, different training modalities, effects of exercise training, possible pathobiological mechanisms of action, and future research questions are discussed.
Keywords:
Exercise training, Pulmonary arterial hypertension, Pulmonary hypertension; Rehabilitation, Training effectsfigures
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